TNGX, Tango Therapeutics, Inc

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CEO:Dr. Malte Peters M.D.

Headquarter: 201 Brookline Avenue, Suite 901, Boston, MA, United States, 02215

Industry: Biotechnology,   Investment Track: Precision Oncology - Protein,   Employees: 137

Business Summary

Tango Therapeutics, Inc., a precision oncology company, focuses on the discovery and development of drugs in defined patient populations with unmet medical need. The company develops methylthioadenosine -cooperative protein arginine methyltransferase 5 (PRMT5) inhibitors, including TNG462, which is in Phase 1/2 clinical trial for treating pancreatic and lung cancer; and TNG456, a brain-penetrant PRMT5 inhibitor for the treatment of glioblastoma. It is developing TNG260, a co-repressor of repressor element-1 silencing transcription inhibitor to reverse the immune evasion effect of serine-threonine kinase (STK) 11 loss-of-function mutations to treat lung cancer. The company was founded in 2017 and is headquartered in Boston, Massachusetts.